The Acadia's interior features a "low and away" instrument panel that enhances the feeling of openness in the front-row seats and provides a commanding outward view. All interior elements feature high-quality, low-gloss materials and attention to fit, finish and flushness. Additional professional grade features include GMC's signature red gauge lighting, thick door glass, flat-blade windshield wipers and strategically placed sound deadening material, which minimize road and wind noise.

The interior can be configured for seven or eight passengers. The second row is available with either a 60/40-split bench (three passengers) design or two captain's chairs (two passengers). The GM-exclusive Smart Slide feature is standard on both second-row configurations and provides a wide space for passengers entering and exiting the third row.

Acadia also offers generous cargo room, including an estimated 117 cu. ft. (3,313 L) when the second- and third-row seats are folded and an estimated 19.7 cu. ft. (557.9 L) of cargo space behind the third-row seat when it's in its upright position - capacity many other SUVs and crossovers cannot come close to matching.

Acadia has a wide range of useful optional and standard equipment, including heated outside mirrors, tri-zone heating and air conditioning system, intermittent rear wiper, ultrasonic parking assist, power liftgate, extended-range remote vehicle starting system, heated windshield washer fluid, an oversized dual SkyScape sunroof, DVD entertainment system, a DVD-based navigation system and Bose 5.1 Surround Sound Audio system. Acadia also offers an exclusive head-up display that projects instrument readouts and other features onto the windshield for easy, eyes-on-the-road reference.